Cesium carbonate → HCID 66885609, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-(1-methylethoxy)-4-nitrophenol (27.3 g), cesium carbonate (90.4 g), 2-bromo-5-(methylsulfonyl)pyridine (32.7 g) and N,N-dimethylformamide (250 mL) was stirred at 100° C. for 4 h. The mixture was concentrated under reduced pressure and water was added to the residue. The resulting brown suspension was filtered to collect a brown solid. The solid was washed with ethanol-hexane to give the title compound (38.82 g, 79%) as a brownish-yellow solid. MS 353 (MH+).

Provenance & Evidence