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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1189181Generated: October 30, 2026

2-Bromo-6-(fluoromethyl)pyridine → HCID 66597937, compound

https://huagongshe.com/reaction/1189181

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-(fluoromethyl)pyridineHCID 10241610—
ReactantHCID 57691784HCID 57691784—
ProductHCID 66597937HCID 6659793717%

Reaction Steps

The title compound was prepared in accordance with the general method of Example 108(C), from 2-bromo-6-(fluoromethyl)-pyridine (204 mg, 1.07 mmol) and 2-but-3-ynyl-2H-indazole (183 mg, 1.07 mmol). The crude residue was purified by flash chromatography (cyclohexane/AcOEt 3:2) to yield 50 mg (0.18 mmol, 17%) of 2-(4-(6-(fluoromethyl)pyridin-2-yl)but-3-ynyl)-2H-indazole as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08674106B2
Source datasetuspto-grants-2014_03
ORD IDord-853dfe0ca63f4396a5f0c6c7c7511a59
Source noteuspto-grants-2014_03