HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorophenol → HCID 86086817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorophenol | HCID 7933 | — |
| Reactant | 4-Pentynoic acid | HCID 22464 | — |
| Product | HCID 86086817 | HCID 86086817 | 95.1% |
Reaction Steps
According to the protocol described in Example 235(B), the reaction between pent-4-ynoic acid (590 mg, 6.0 mmol) and 3-chlorophenol (771 mg, 6.0 mmol) afforded 1.19 g of 3-chlorophenyl pent-4-ynoate (Yield: 95%) as colorless-oil. Purification over silicagel chromatography (prepacked 25 g silicagel column, Cyclohexane/AcOEt:90/10 as eluent)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674106B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-8f3eb96ff86041f0aa7f99868d3dd287 |
| Source note | uspto-grants-2014_03 |