Nitrogen → HCID 86664918, compound

Participants

Reaction Conditions

Reaction Steps

In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of the crude 2-(3-acetyl-benzyl)-oxazole-4-carbonyl chloride in dry acetone (13.5 mL) was cooled to 0° C. and a solution of sodium azide (210 mg, 3.20 mmol) in H2O (1.7 mL) was added dropwise. The reaction mixture was stirred at 0° C. for 1 h. The mixture was concentrated under reduced pressure (coevaporation with toluene) then dissolved in CH2Cl2 and filtered. The filtrate was concentrated under reduced pressure to give the title compound as an orange oil. LC-MS-conditions 02: tR=0.91 min [M+AcCN+H]+=312.31.

Provenance & Evidence