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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 118955Generated: October 25, 2026

Benzene, 1-(chloromethyl)-2-fluoro- → 1-Benzyl-4-(2-fluorobenzyl)piperidin-4-ol

https://huagongshe.com/reaction/118955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-(chloromethyl)-2-fluoro-HCID 9580—
Reactant1-Benzyl-4-piperidoneHCID 19220—
ReactantHydrogen iodideHCID 24841—
ReactantMagnesiumHCID 5462224—
Product1-Benzyl-4-(2-fluorobenzyl)piperidin-4-olHCID 12733224—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-3bd5f8eadeb7409a882259485e3ad3be
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)