Sodium Hydroxide → HCID 53246738, compound

Participants

Reaction Steps

General procedure I (step 1 and 2) was followed using ethyl 2-(2,5-dimethyl-3-(2-(morpholinosulfonyl)benzoyl)-1H-pyrrol-1-yl)acetate (0.0500 g, 0.115 mmol) and 1M sodium hydroxide solution (0.345 ml, 0.345 mmol) to afford 2-(2,5-dimethyl-3-(2-(morpholinosulfonyl)benzoyl)-1H-pyrrol-1-yl)acetic acid (22.8 mg, 0.0560 mmol, 49% yield). 1H NMR (400 MHz, CDCl3): δ (ppm) 7.85 (d, 1H), 7.62 (ddd, 1H), 7.56 (app. td, 1H), 5.72 (s, 1H), 4.55 (s, 2H), 3.68-3.70 (m, 4H), 3.13-3.16 (m, 4H), 2.45 (s, 3H), 2.09 (s, 3H).

Provenance & Evidence