Sodium Hydroxide → HCID 53246858, compound

Participants

Reaction Steps

was followed using methyl 2-(2,5-dimethyl-3-phenyl-4-(2-(pyrrolidin-1-ylsulfonyl)phenylthio)-1H-pyrrol-1-yl)acetate (24.6 mg, 0.0510 mmol) and 1M sodium hydroxide (0.152 ml, 0.152 mmol) to afford 2-(2,5-dimethyl-3-phenyl-4-(2-(pyrrolidin-1-ylsulfonyl)phenylthio)-1H-pyrrol-1-yl)acetic acid (15.2 mg, 0.0320 mmol, 64% yield) as a tan solid. 1H NMR (400 MHz, CDCl3): δ (ppm) 7.89 (dd, 1H), 7.07-7.22 (m, 7H), 6.93 (dd, 1H), 4.73 (s, 2H), 3.19-3.23 (m, 4H), 2.27 (s, 3H), 2.23 (s, 3H), 1.61-1.64 (m, 4H).

Provenance & Evidence