HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-Amino-2,4-dichlorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1-Chloro-N,N-2-trimethylpropenylamine | HCID 640792 | — |
| Reactant | 3-Amino-2,4-dichlorobenzoic acid | HCID 15278234 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Amino-2,4-dichlorobenzamide | HCID 58625467 | — |
Reaction Steps
(1-Chloro-2-methyl-propenyl)-dimethyl-amine (16.1 mL, 116 mmol) is added to 3-amino-2,4-dichloro-benzoic acid (20.0 g, 97.1 mmol) in THF (320 mL). After 4 h at rt the mixture is added dropwise to conc NH3 (320 mL) and stirred at rt overnight. The reaction mixture is concentrated, cooled and filtered. The filtercake is dried to give the sub-title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-7fbb3ddf360140ceb0fd77282a1fbc2b |
| Source note | uspto-grants-2014_03 |