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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1189623Generated: October 31, 2026

Pivaloyl chloride → N-(3-amino-4-chloro-2-fluorobenzyl)pivalamide

https://huagongshe.com/reaction/1189623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivaloyl chlorideHCID 62493—
ReactantHCID 56839970HCID 56839970—
ProductN-(3-amino-4-chloro-2-fluorobenzyl)pivalamideHCID 5683997836%

Reaction Steps

The sub-title compound is prepared from crude 3-amino-4-chloro-2-fluoro-benzylamine, 2,2-dimethyl-propionic acid chloride and TEA in analogy to example Ae.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08674113B2
Source datasetuspto-grants-2014_03
ORD IDord-7d312bad9c3f41f9949ce539566b1f93
Source noteuspto-grants-2014_03