HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178447331, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | N-(2,4-Difluoro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide | HCID 56840193 | — |
| Reactant | HCID 178507776 | HCID 178507776 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178447331 | HCID 178447331 | — |
Reaction Steps
The title compound is prepared in analogy to 2c from N-(trans-4-trifluoromethyl-cyclohexyl)-2-(4-fluoro-piperidinyl)-4,5-diamino-benzoic acid amide (50 mg, 0.12 mmol), and N-(2,4-difluoro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide (70 mg, 0.24 mmol), DIC (30 μL) and DMF (2.0 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-4b55b63bdb6744dfa39ccd114214e583 |
| Source note | uspto-grants-2014_03 |