HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178481219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | N-[(2,4-dichloro-3-isothiocyanatophenyl)methyl]-2,2-dimethylpropanamide | HCID 56840192 | — |
| Reactant | HCID 178482235 | HCID 178482235 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178481219 | HCID 178481219 | — |
Reaction Steps
The title compound is prepared in analogy to 6c from N-(trans-4-trifluoromethyl-cyclohexyl)-2-[3,3-difluoro-pyrrolidinyl]-4-methylamino-5-amino-benzoic acid amide (140 mg, 0.33 mmol), and N-(2,4-dichloro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide (93 mg, 0.29 mmol), DIC (63 μL) and MeCN (3.0 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-0cfacd6a0db74e95a55c2003414aa0d2 |
| Source note | uspto-grants-2014_03 |