Tetrahydrofuran → HCID 67957361, compound

Participants

Reaction Steps

A mixture of N-(2,2,2-trifluoroethyl)-2-[4-(1-hydroxy-1-methyl-ethyl)-piperidinyl]-4-methylamino-5-nitro-benzoic acid amide (crude product from the reaction above), Pd/C (10 mg), THF (5 ml) and MeOH (5 ml) is stirred under 3 bar H2-atmosphere for 7 h. The mixture is filtered and the filtrate is concentrated and directly used in the next step.

Provenance & Evidence