HCID 86666471, compound → HCID 86666472, compound

Participants

Reaction Steps

A mixture of (R)—N-(4-trifluoromethoxyphenyl)-2-[3-fluoro-pyrrolidinyl]-4-(2,2-difluoro-ethylamino)-5-nitro-benzoic acid amide (100 mg, 0.20 mmol), Ra—Ni (40 mg) and THF (10 mL) is stirred under 3 bar H2-atmosphere overnight. The mixture is filtered, and the filtrate is concentrated. Yield: 94 mg. HPLC Rt=1.41 min (method A). MS m/z: 463 [M+H]+.

Provenance & Evidence