Stannous Chloride → HCID 178482256, compound

Participants

Reaction Steps

A mixture of N-(trans-4-trifluoromethyl-cyclohexyl)-2-[N-methyl-N-cyanomethyl-amino]-4-methylamino-5-nitro-benzoic acid amide (50 mg, 0.12 mmol), SnCl2 (134 mg 0.59 mmol and 5 mL EtOAc is stirred at reflux for 4 h. The mixture is diluted with EtOAc, washed with sat aq NaHCO3, filtered through a pad of celite and the celite pad is washed with EtOAc. The combined organic phases are dried with Na2SO4, filtered and concentrated.

Provenance & Evidence