HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178429796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | N-[(2,4-dichloro-3-isothiocyanatophenyl)methyl]-2,2-dimethylpropanamide | HCID 56840192 | — |
| Reactant | HCID 178482278 | HCID 178482278 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178429796 | HCID 178429796 | — |
Reaction Steps
The title compound is prepared in analogy to 6c from N-(trans-4-trifluoromethyl-cyclohexyl)-2-[3-aza-bicyclo[3.1.0]hex-3-yl]-3-methyl-4-methylamino-5-amino-benzoic acid amide (80 mg, 0.195 mmol), and N-(2,4-dichloro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide (62 mg, 0.19 mmol), DIC (36 μL) and dioxane (5.0 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674113B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-8851d4f0c6134b119cffa9dcdedb24b0 |
| Source note | uspto-grants-2014_03 |