Methanol → HCID 67957429, compound

Participants

Reaction Steps

A mixture of N-(4-trifluoromethoxyphenyl)-2-(morpholinyl)-4-(2-hydroxy-2-methyl-propylamino)-5-nitro-benzoic acid amide (100 mg, 0.20 mmol), Pd/C (50 mg), MeOH (3.5 mL) and THF (10 mL) is stirred under 4 bar H2-atmosphere overnight. The mixture is filtered, and the filtrate is concentrated. Yield: 94 mg. HPLC Rt=1.36 min (method H). MS m/z: 468 [M+H]+.

Provenance & Evidence