HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimedone → Cyclohexanone, 3,3-dimethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimedone | HCID 31358 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Solvent | Ethylene Glycol | HCID 174 | — |
| Product | Cyclohexanone, 3,3-dimethyl- | HCID 76322 | 4% |
Reaction Steps
Sasson et al. achieved reduction of dimedone via transfer hydrogenation in ethylene glycol as hydrogen donor in the presence of the homogenous catalyst RuCl2 (PPh3)3. Among a number of different reduction products 3,3-dimethylcyclohexan-1-one was obtained only in 4% yield which is an unacceptable low selectivity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08674143B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-b3dd283b1c4e4d09aa9d53628da71494 |
| Source note | uspto-grants-2014_03 |