Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-(4-Methylpiperazin-1-yl)pyridin-3-amine → 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-Pyridin-3-yl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-(4-Methylpiperazin-1-yl)pyridin-3-amine | HCID 2763390 | — |
| 반응물 | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)phenyl]-amide | HCID 44515669 | — |
| 생성물 | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-Pyridin-3-yl]-amide | HCID 44515672 | — |
반응 단계
The title compound was prepared in analogy to the procedure described in Step 14.1 but stirring the reaction mixture for 20 h at rt and using 6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine (prepared as described in Example 33 but using N-methyl-piperazine in Step 33.2) and 8-isoquinolin-4-yl-quinoxaline-5-carboxylic acid (Example 52). Title compound: ESI-MS: 476.1 [M+H]+; tR=1.98 min (System 1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08674099B2 |
| 출처 데이터셋 | uspto-grants-2014_03 |
| ORD ID | ord-44b2e4e3b6954ae0ba8f0f61f7ae9fb2 |
| 출처 메모 | uspto-grants-2014_03 |