HCID 67296497, compound → HCID 67296717, compound

HRID 1189950Notes

Reaction equation

HRID 1189950 reaction equation
[OH:1][CH:2]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][OH:25])[CH:14]=1)[CH2:3][CH2:4][NH:5][C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:10])[CH3:9]>O=[Mn]=O>[OH:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][NH:19][C:15]1[CH:14]=[C:13]([C:2](=[O:1])[CH2:3][CH2:4][NH:5][C:6](=[O:12])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 67296497HCID 67296497, compound

Product 1

HCID 67296717HCID 67296717, compound

Reagents, catalysts & solvents 1

HCID 14801Manganese dioxideCatalyst

Procedure

MnO2 oxidation of tert-butyl 3-hydroxy-3-(3-(5-hydroxypentylamino)phenyl)propylcarbamate following the method used in Example 12 gives tert-butyl 3-(3-(5-hydroxypentylamino)phenyl)-3-oxopropylcarbamate.

Sources & evidence

ORD record
ord-ee15b869efd846e5bcbcacb0b75a0a05
Source dataset
uspto-grants-2014_03
Patent number
US08674137B2

Reaction notes

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