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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1189960Generated: November 1, 2026

1-Oxaspiro(2.4)heptane → 2-(3-(3-(((1-Hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dione

https://huagongshe.com/reaction/1189960

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Oxaspiro(2.4)heptaneHCID 637991—
Reactant2-(3-(3-Aminophenyl)propyl)isoindoline-1,3-dioneHCID 22124964—
Product2-(3-(3-(((1-Hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dioneHCID 67296688—

Reaction Steps

Reaction between 1-oxaspiro[2.4]heptane and 2-(3-(3-aminophenyl)propyl)isoindoline-1,3-dione gives 2-(3-(3-(((1-hydroxycyclopentyl)methyl)amino)phenyl)propyl)isoindoline-1,3-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08674137B2
Source datasetuspto-grants-2014_03
ORD IDord-5111bba99c3a45b1a6003d917669dd69
Source noteuspto-grants-2014_03