Tert-butyl 3-(3-(cyclohexylmethylamino)phenyl)propylcarbamate → Tert-butyl 3-(3-(1-propylbutylsulfonamido)phenyl)propylcarbamate

HRID 1189964Notes

Reaction equation

HRID 1189964 reaction equation
C1(C[NH:8][C:9]2[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22])[CH:12]=[CH:13][CH:14]=2)CCCCC1.[CH3:26][CH2:27][CH2:28][CH:29]([S:33](Cl)(=[O:35])=[O:34])[CH2:30][CH2:31][CH3:32]>>[CH2:28]([CH:29]([S:33]([NH:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH:12]=[CH:13][CH:14]=1)(=[O:35])=[O:34])[CH2:30][CH2:31][CH3:32])[CH2:27][CH3:26]

Participants

3

Reactant 2

HCID 59317002Tert-butyl 3-(3-(cyclohexylmethylamino)phenyl)propylcarbamateHCID 62084556Heptane-4-sulfonyl chloride

Product 1

HCID 68525264Tert-butyl 3-(3-(1-propylbutylsulfonamido)phenyl)propylcarbamate

Procedure

Sulfonation of aniline 17 by heptane-4-sulfonyl chloride following the method used in Example 6 gives tert-butyl 3-(3-(1-propylbutylsulfonamido)phenyl)propylcarbamate.

Sources & evidence

ORD record
ord-fe60ddf6b2b4476a92edaf548a66879f
Source dataset
uspto-grants-2014_03
Patent number
US08674137B2

Reaction notes

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