2,2-Diethyloxirane → 3-(3-(2-Ethyl-2-hydroxybutylamino)phenyl)-3-hydroxypropanenitrile

HRID 1189967Notes

Reaction equation

HRID 1189967 reaction equation
[CH2:1]([C:3]1([CH2:6][CH3:7])[CH2:5][O:4]1)[CH3:2].[NH2:8][C:9]1[CH:10]=[C:11]([CH:15]([OH:19])[CH2:16][C:17]#[N:18])[CH:12]=[CH:13][CH:14]=1>>[CH2:1]([C:3]([OH:4])([CH2:6][CH3:7])[CH2:5][NH:8][C:9]1[CH:10]=[C:11]([CH:15]([OH:19])[CH2:16][C:17]#[N:18])[CH:12]=[CH:13][CH:14]=1)[CH3:2]

Participants

3

Reactant 2

HCID 2959712,2-DiethyloxiraneHCID 593169603-(3-Aminophenyl)-3-hydroxypropanenitrile

Product 1

HCID 672965933-(3-(2-Ethyl-2-hydroxybutylamino)phenyl)-3-hydroxypropanenitrile

Procedure

Reaction between 2,2-diethyloxirane and aniline 12 gives 3-(3-(2-ethyl-2-hydroxybutylamino)phenyl)-3-hydroxypropanenitrile.

Sources & evidence

ORD record
ord-cbb7afb76fb6457c9786cfe9c64b4b1f
Source dataset
uspto-grants-2014_03
Patent number
US08674137B2

Reaction notes

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