4-(Morpholinomethyl)aniline → HCID 58994529, compound

HRID 1190168Notes

Reaction equation

HRID 1190168 reaction equation
[N:1]1([CH2:7][C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[C:15]1(B(O)O)[CH2:20][CH2:19][CH2:18][CH2:17][CH:16]=1>>[C:15]1([C:12]2[CH:13]=[C:8]([CH2:7][N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)[CH:9]=[CH:10][C:11]=2[NH2:14])[CH2:20][CH2:19][CH2:18][CH2:17][CH:16]=1

Participants

3

Reactant 2

HCID 7768514-(Morpholinomethyl)anilineHCID 38629021-Cyclohexenylboronic acid

Product 1

HCID 58994529HCID 58994529, compound

Procedure

This compound was prepared from 4-morpholin-4-ylmethyl-phenylamine by brominating according to the procedure in Example 33, step (b), followed by Suzuki coupling to 1-cyclohexen-1-yl-boronic acid according to the procedure in Example 1, step (e). Mass spectrum (ESI, m/z): Calcd. for C17H24N2O, 273.2 (M+H). found 272.7

Sources & evidence

ORD record
ord-9399512e07ad42f286a50bc99e1f6bfa
Source dataset
uspto-grants-2014_03
Patent number
US08674100B2

Reaction notes

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