N-bromobutanimide → HCID 58994357, compound

HRID 1190183Notes

Reaction equation

HRID 1190183 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH:11][CH2:12][CH2:13][CH2:14][OH:15])=[O:10])=[CH:4][CH:3]=1.C1C(=O)N([Br:23])C(=O)C1>>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([NH:11][CH2:12][CH2:13][CH2:14][OH:15])=[O:10])=[CH:6][C:7]=1[Br:23]

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 43345830HCID 43345830, compound

Product 1

HCID 58994357HCID 58994357, compound

Procedure

The title compound was prepared from 2-(4-amino-phenyl)-N-(3-hydroxy-propyl)-acetamide (as prepared in the previous step) and NBS according to the procedure in Example 7, step (c). Mass spectrum (ESI, m/z): Calcd. for C1H15BrN2O2, 287.0 (M+H). found 287.0.

Sources & evidence

ORD record
ord-d194e7adc1ec44a6aa3cc340edfb2722
Source dataset
uspto-grants-2014_03
Patent number
US08674100B2

Reaction notes

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