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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 119032Generated: October 28, 2026

Dimethyl Sulfoxide → 2,2-dimethyl-3-[2'-oxo-5'-[2-(phenylmethoxymethyl)pyrrolidin-1-yl]sulfonylspiro[1,3-dioxane-2,3'-indole]-1'-yl]propanenitrile

https://huagongshe.com/reaction/119032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant3-Chloro-2,2-dimethylpropanenitrileHCID 14713915—
Reactant5'-[2-(phenylmethoxymethyl)pyrrolidin-1-yl]sulfonylspiro[1,3-dioxane-2,3'-1H-indole]-2'-oneHCID 178517307—
Product2,2-dimethyl-3-[2'-oxo-5'-[2-(phenylmethoxymethyl)pyrrolidin-1-yl]sulfonylspiro[1,3-dioxane-2,3'-indole]-1'-yl]propanenitrileHCID 178449169—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-a0002ffc554240c892ffd79a430090ce
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)