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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1190381Generated: October 31, 2026

(2S)-2-methylpyrrolidine → HCID 58203994, compound

https://huagongshe.com/reaction/1190381

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-methylpyrrolidineHCID 6999702—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58203994HCID 58203994—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with (S)-2-methylpyrrolidine (1.2 equiv) to give 171 (14.8 mg, M+1 381.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08673952B2
Source datasetuspto-grants-2014_03
ORD IDord-651e3cba35054b54b50de433273a46cd
Source noteuspto-grants-2014_03