(2-Methoxyethyl)(methyl)amine → HCID 58204277, compound

HRID 1190392Notes

Reaction equation

HRID 1190392 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:22]=[CH:21][C:9]3[C:10]4[N:11]=[C:12]([C:18](O)=[O:19])[S:13][C:14]=4[CH2:15][CH2:16][O:17][C:8]=3[CH:7]=2)[CH:3]=[N:2]1.[CH3:23][O:24][CH2:25][CH2:26][NH:27][CH3:28]>>[CH3:23][O:24][CH2:25][CH2:26][N:27]([CH3:28])[C:18]([C:12]1[S:13][C:14]2[CH2:15][CH2:16][O:17][C:8]3[CH:7]=[C:6]([C:4]4[CH:3]=[N:2][NH:1][CH:5]=4)[CH:22]=[CH:21][C:9]=3[C:10]=2[N:11]=1)=[O:19]

Participants

3

Reactant 2

HCID 300977(2-Methoxyethyl)(methyl)amineHCID 582038838-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid

Product 1

HCID 58204277HCID 58204277, compound

Procedure

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with 2-methoxy-N-methylethanamine (1.2 equiv) to give 182 (15.1 mg, M+1 385.1)

Sources & evidence

ORD record
ord-10c873736a7943428649fba73787d8ae
Source dataset
uspto-grants-2014_03
Patent number
US08673952B2

Reaction notes

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