Hydrochloric Acid → HCID 70944851, compound

Participants

Reaction Steps

3-Methyl-4-(4-methylpiperazin-1-yl)-5-(morpholin-4-ylmethyl)aniline (79 mg, 0.26 mmol) and 4,7-dichloroquinoline (56 mg, 1.1 eq) were refluxed overnight in 5 mL of acetonitrile with 0.78 mL of HCl 1M. The reaction mixture was then evaporated and purified by flash chromatography (DCM/MeOH/NH4OH//9/1/0.1) to yield expected compound as a pale yellow solid (75 mg, 62% yield). m/z (ESI) 466.4 [M+H]+.

Provenance & Evidence