Hydrochloric Acid → HCID 70944817, compound

Participants

Reaction Steps

3,5-Bis[(pyrrolidin-1-yl)carbonyl]aniline (287 mg, 1.0 mmol) and 4,7-dichloroquinoline (198 mg, 1 eq) were refluxed in 20 mL of ethanol and 2 mL of HCl 1M for 12 h. The reaction mixture was then evaporated. The residue was purified by flash chromatography (DCM/MeOH//9/1) to yield expected compound as a yellow powder (2.90 g, 78% yield). m/z (ESI) 449.1 [M+H]+.

Provenance & Evidence