4,7-Dichloroquinoline → HCID 11406039, compound

Participants

Reaction Steps

5-amino-2-(morpholin-4-ylmethyl)phenol (58 mg, 0.28 mmol) and 4,7-dichloroquinoline (61 mg, 1.1 eq) were refluxed overnight in 1 mL of EtOH. The reaction mixture was then evaporated and purified by flash chromatography (DCM/MeOH/NH4OH 9:1:0.1) to yield expected compound as a brown solid (41 mg, 40% yield). LC-MS: m/z (ESI) 470.1-472.1 [M+H]+

Provenance & Evidence