4,7-Dichloroquinoline → HCID 15654508, compound

Participants

Reaction Steps

3-aminophenol (5.00 g, 25.25 mmol) and 4,7-dichloroquinoline (2.76 g, 1 eq) were refluxed overnight in 5 mL of EtOH. The reaction mixture was then evaporated and purified by flash chromatography (DCM/MeOH/NH4OH 9:1:0.1) to yield expected compound as a pale yellow solid (6.8 g, 99% yield). LC-MS: m/z (ESI) 271.2 [M+H]+;

Provenance & Evidence