HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 58319355, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 53780239 | HCID 53780239 | — |
| Reactant | HCID 67238045 | HCID 67238045 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58319355 | HCID 58319355 | — |
Reaction Steps
Into a round-bottomed flask under nitrogen are introduced 300 mg of the acid obtained in step 3a) in 30 ml of DMF, 246 mg of 4-(4-chlorophenyl)piperidine-4-carboxamide (prepared according to the procedure described in patent application US 2005/0070549, in particular in Example 460, paragraphs 1394 to 1397), 0.62 ml of DIPEA and 250 mg of TBTU.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08680102B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-49922945fa5949f598d8fbe35306343c |
| Source note | uspto-grants-2014_03 |