Ammonia → HCID 58495659, compound

Participants

Reaction Steps

To a slurry of Raney Nickel (0.2 g, 50% in water) in ethanol (35 mL) add a solution of 6-[(3,3-dimethylcyclohexyl)thio]-pyridine-3-carbonitrile (0.37 g, 1.5 mmol) in ethanol (5 mL) followed by aqueous ammonia (0.88 M, 2 mL) and hydrogenate the mixture in a Parr shaker at 60 psi for 3 h. Filter the mixture through Celite® washing the filter cake with ethanol. Remove the solvent in vacuo to obtain the title compound as an oil (0.2 g, 53%).

Provenance & Evidence