Ammonia → HCID 58495667, compound

Participants

Reaction Steps

To a slurry of Raney Nickel (0.2 g, 50% in water) in ethanol (35 mL) add a solution of 4-[(3,3-dimethylcyclohexyl)-thio]-benzonitrile (0.35 g, 1.43 mmol) in ethanol (5 mL) followed by aqueous ammonia (0.88 M, 2 mL) and hydrogenate the mixture in a Parr shaker at 60 psi for 3 h. Filter the mixture through Celite® washing the filter cake with ethanol. Remove the solvent in vacuo to obtain the title compound as a pale yellow oil (0.24 g, 67%).

Provenance & Evidence