Ammonia → HCID 58495619, compound

Participants

Reaction Steps

To a slurry of Raney Nickel (0.25 g, 50% in water) in ethanol (40 mL) add a solution of 4-[(3,3-dimethylcyclohexyl)thiomethyl]-benzonitrile (0.4 g, 1.54 mmol) in ethanol (5 mL) followed by aqueous ammonia (0.88 M, 2.5 mL) and hydrogenate the mixture in a Parr shaker at 60 psi for 3 h. Filter the mixture through Celite® washing the filter cake with ethanol. Remove the solvent in vacuo to obtain the title compound as an oil (0.4 g, 100%).

Provenance & Evidence