Pyridine → 1-(1-Naphthoyl)-3-(RS)-(4-(4-fluorophenyl)piperidinylmethyl)-4-(SR)-(cyclopropyl)pyrrolidine
Reaction equation
[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH:15]3[CH2:16][NH:17][CH2:18][CH:19]3[CH:20]3[CH2:21][CH2:22]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1.[c:29]1([C:39](=[O:40])[Cl:41])[cH:30][cH:31][cH:32][c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]12.[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH:15]3[CH2:16][N:17]([C:39]([c:29]4[cH:30][cH:31][cH:32][c:33]5[cH:34][cH:35][cH:36][cH:37][c:38]45)=[O:40])[CH2:18][CH:19]3[CH:20]3[CH2:21][CH2:22]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-ddeda64c2adc4b1f9927ab7907551443
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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