1,4-Dioxane → 5-(4-(4-(3-Fluorobenzyloxy)-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl)-furan-3-carbaldehyde

HRID 119123Notes

Reaction equation

HRID 119123 reaction equation
[CH2:28]([Sn:29]([CH2:30][CH2:31][CH2:32][CH3:40])([c:33]1[cH:34][c:35]([CH:38]=[O:39])[cH:36][o:37]1)[CH2:41][CH2:42][CH2:43][CH3:44])[CH2:45][CH2:46][CH3:47].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[NH:10][c:11]2[cH:12][cH:13][c:14]([O:17][CH2:18][c:19]3[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:26][n:27]1.[O:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1>>[c:2]1(-[c:33]2[cH:34][c:35]([CH:38]=[O:39])[cH:36][o:37]2)[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[NH:10][c:11]2[cH:12][cH:13][c:14]([O:17][CH2:18][c:19]3[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:26][n:27]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 109599912-(Tributylstannyl)furan-4-carboxaldehydeHCID 21952062(6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine

Product 1

HCID 219520885-(4-(4-(3-Fluorobenzyloxy)-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl)-furan-3-carbaldehyde

Sources & evidence

ORD record
ord-edd99fa882b641d888b2980b222881a8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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