Water → HCID 86634371, compound

Participants

Reaction Steps

To a solution of the compound 4 (1.22 g) in methanol (20 mL), potassium carbonate (0.91 g) was added. The reaction mixture was stirred at room temperature for overnight. The reaction mixture was added water and extracted with ethyl acetate. The extract was washed with saturated brine, dried over anhydrous magnesium sulfate and then concentrated. The obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=10:0→4:1→3:1) to obtain the title compound (0.66 g) having the following physical properties.

Provenance & Evidence