Tetrahydrofuran → HCID 69009230, compound

Participants

Reaction Conditions

Reaction Steps

Benzyloxycarbonyl chloride (2.55 mL) was added dropwise to the compound 12 (3.40 g), tetrahydrofuran (50 mL) and triethylamine (4.15 mL) with stirring at 0° C. The reaction solution was stirred at 0° C. for 20 minutes, added water and extracted with ethyl acetate. The extract was dried over anhydrous magnesium sulfate and then concentrated. The obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=1:1→0:1) to obtain the title compound (4.81 g) having the following physical properties.

Provenance & Evidence