Dimethyl Sulfoxide → HCID 86634387, compound

Participants

Reaction Steps

To a solution of the compound 39 (174 mg), dimethylsulphoxide (3 mL) and triethylamine (1.5 mL) in dichloromethane (3 mL) with stirring, sulfur trioxide pyridine complex (212 mg) was added into the solution at room temperature. The reaction solution was stirred for 2 hours, added water and extracted with a mixture solution of hexane/ethyl acetate. The extract was washed with water, aqueous 5% potassium bisulfate solution, water and saturated brine, dried over anhydrous magnesium sulfate, concentrated and obtained the title compound (171 mg) having the following physical properties.

Provenance & Evidence