Ammonium Chloride → HCID 69670903, compound

Participants

Reaction Steps

To a suspension of 1-benzenesulfonyl-5-formyl-2-phenylindole (224 mg) in ethanol (2.5 mL) was added sodium borohydride (11.7 mg), and the mixture was stirred at room temperature for one hour. A saturated aqueous ammonium chloride solution was added to the reaction mixture and the resulting mixture was extracted with ethyl acetate. The organic layer was washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluting solvent: ethyl acetate-hexane) to obtain the title compound (173 mg).

Provenance & Evidence