4-Ethylpyridin-2-amine → HCID 58869959, compound

Participants

Reaction Steps

The product from Example 1, Part C (0.3 g, 0.93 mmol) and 2-amino-4-ethylpyridine (0.171 g, 1.4 mmol) were converted to the title compound by the method described in Part B of Example 16 (121 mg, 30%). 1H NMR (300 MHz, CDCl3) δ 8.53 (broad s, 1H); 8.15 (d, J=5.16 Hz, 1H); 7.99 (s, 1H); 7.23 (d, J=8.4 Hz, 2H); 6.92 (m, 1H); 6.84 (d, J=8.5 Hz, 2H); 5.11 (d, J=15 Hz, 1H); 4.61 (s, 1H); 4.16 (d, 15 Hz, 1H); 3.77 (s, 3H); 2.90 (s, 2H); 2.67 (q, J=7.4 Hz, 2H); 1.95 (s, 3H); 1.84 (s, 3H); 1.27 (t, J=7.6 Hz, 3H). MS: m/z (MH+) 426.

Provenance & Evidence