Isopropyl iodide → 5-Bromo-1-isopropylpyridin-2(1H)-one

HRID 1191819Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[CH:9](I)([CH3:11])[CH3:10]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5](=[O:8])[N:6]([CH:9]([CH3:11])[CH3:10])[CH:7]=1

Participants

Reactant 2

HCID 6362Isopropyl iodide

HCID 5995285-Bromo-2-hydroxypyridine

Product 1

HCID 467388205-Bromo-1-isopropylpyridin-2(1H)-one

Procedure

5-bromo-1-isopropylpyridin-2(1H)-one was prepared from 5-bromopyridin-2(1H)-one and isopropyl iodide following a procedure analogous to that described in Example 59 Step 1.

Sources & evidence

ORD record: ord-1fa4c1523a5f4e92bd844a243f19f039
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08680093B2

Reaction notes

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