Isopropyl iodide → 4-iodo-1-isopropylpyridin-2(1H)-one

HRID 1191832Notes

Reaction equation

[I:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[CH:3]=1.[CH:9](I)([CH3:11])[CH3:10]>>[I:1][C:2]1[CH:7]=[CH:6][N:5]([CH:9]([CH3:11])[CH3:10])[C:4](=[O:8])[CH:3]=1

Participants

Reactant 2

HCID 6362Isopropyl iodide

HCID 205825354-Iodo-1,2-dihydropyridin-2-one

Product 1

HCID 667359104-iodo-1-isopropylpyridin-2(1H)-one

Procedure

4-iodo-1-isopropylpyridin-2(1H)-one was prepared from 4-iodopyridin-2(1H)-one and isopropyl iodide following a procedure analogous to that described in Example 59 Step 1.

Sources & evidence

ORD record: ord-7400b24cedb847fe93f860305b9915cd
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08680093B2

Reaction notes

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