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ubiquitin cross-reactive protein → Sodium proglumide
参与物
| 角色 | 名称 | HCID | 投料 |
|---|---|---|---|
| 反应物 | ubiquitin cross-reactive protein | HCID 311 | — |
| 反应物 | 酸性橙 86 | HCID 700 | — |
| 反应物 | 丙谷胺 | HCID 4922 | — |
| 反应物 | 钠 | HCID 5360545 | — |
| 溶剂 | 聚[6-[4-(4-氰基苯基)苯氧基]己基甲基丙烯酸酯] | HCID 962 | — |
| 产物 | Sodium proglumide | HCID 67566730 | — |
反应步骤
In another embodiment, a composition for IV injection can be made as follows: add 4263 g of the sodium salt of proglumide to 15 L of water and 93 g of ethanolamine and stir until a clear solution is obtained. After buffering with citric acid, the solution is diluted to a volume of 30 L, then filtered under pressure in an inert gas into 40,000 glass vials which are sterilized under heat, yielding 40,000 vials each containing 106.6 mg sodium proglumide, equivalent to 100 mg proglumide.
来源与证据
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 专利号 | US08680145B1 |
| 来源数据集 | uspto-grants-2014_03 |
| ORD ID | ord-ee737652bf5048daa246a908955b71cd |
| 来源说明 | uspto-grants-2014_03 |