2-Naphthalenethiol → HCID 46932051, compound

HRID 1192035Notes

Reaction equation

HRID 1192035 reaction equation
Cl[C:2]1[S:6][C:5]([C:7](=[O:9])[CH3:8])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[CH:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][C:14]=1[SH:23]>>[CH:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][C:14]=1[S:23][C:2]1[S:6][C:5]([C:7](=[O:9])[CH3:8])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 70582-NaphthalenethiolHCID 5211051-(5-Chloro-4-nitrothiophen-2-yl)ethan-1-one

Product 1

HCID 46932051HCID 46932051, compound

Procedure

Prepared according to the procedure described as in Step B for example 1 from 1-(5-Chloro-4-nitro-2-thienyl)ethanone (0.502 g, 2.45 mmol) and naphthalene-2-thiol (0.392 g, 2.45 mmol). The title compound was obtained as a cream colored solid (0.585 g, 73% yield). 1H NMR (300 MHz, CDCl3) δ: 8.23 (1H, m), 8.09 (1H, s), 7.99 (1H, d), 7.92 (2H, m), 7.63 (3H, m), 2.46 (3H, s).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a320a68ca07241b78485a6ec88064fda
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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