1-(5-Chloro-4-nitrothiophen-2-yl)ethan-1-one → HCID 46932055, compound

HRID 1192040Notes

Reaction equation

HRID 1192040 reaction equation
Cl[C:2]1[S:6][C:5]([C:7](=[O:9])[CH3:8])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[C:13]1([C:19]2[CH:24]=[CH:23][C:22]([SH:25])=[CH:21][CH:20]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[N+:10]([C:3]1[CH:4]=[C:5]([C:7](=[O:9])[CH3:8])[S:6][C:2]=1[S:25][C:22]1[CH:21]=[CH:20][C:19]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:24][CH:23]=1)([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 5211051-(5-Chloro-4-nitrothiophen-2-yl)ethan-1-oneHCID 27604144-Phenylbenzene-1-thiol

Product 1

HCID 46932055HCID 46932055, compound

Procedure

Prepared according to the procedure described for example 1 from 1-(5-Chloro-4-nitro-2-thienyl)ethanone (82 mg, 0.4 mmol) and 4-phenylbenzenthiol (74 mg, 0.4 mmol). The title compound was obtained as a solid (30 mg, 21% yield). 1H NMR (400 MHz, CDCl3) δ: 8.09 (1H, s), 7.74 (2H, m) 7.65 (2H, m), 7.52 (2H, m), 7.44 (2H, m), 2.49 (3H, s). MS m/z: 355.9 [M+H]+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b764feccda0343b6b3ce0b6e5d71dba6
Source dataset
uspto-grants-2014_03
Patent number
US08680139B2

Reaction notes

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