Potassium Carbonate → HCID 46932057, compound

Participants

Reaction Steps

To a solution of 1-(5-Chloro-4-nitro-2-thienyl)ethanone (0.209 g, 1 mmol) in N,N-dimethylformide (4 mL), was added 3,5-dichloro-1-oxido-pyridin-1-ium-4-thiol sodium salt (0.2 g, 1 mmol) and potassium carbonate (0.348 g, 2.56 mmol). The resulting reaction mixture was stirred at ambient temperature for 4 hours. The reaction mixture was poured onto ice (5 mL). After stirring for 10 minutes the solid which formed was collected by filtration and washed with water (10 mL) and air dried. The crude solid product was purified by silica gel flash chromatography using a mixture of 90:10 dichloromethane and methanol as eluent to afford the title product as a yellow solid (0.23 g, 63% yield). 1H NMR (400 MHz, d6-DMSO) δ: 8.93 (1H, s) 8.54 (1H, s), 2.54 (3H, s). MS m/z: 363.0 [M+H]+.

Provenance & Evidence