2-Fluoroethyl bromide → Benzyl 3-[[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

HRID 119208Notes

Reaction equation

HRID 119208 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[c:17]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[CH2:23][CH:24]2[O:25][CH2:26][CH3:27])[n:28][c:29]1[CH2:30][CH3:31].[Cl:32][c:33]1[c:34](-[c:40]2[n:41][c:42]([CH2:65][CH3:66])[c:43]([NH:48][CH:49]3[CH2:50][N:51]([C:55](=[O:56])[O:57][CH2:58][c:59]4[cH:60][cH:61][cH:62][cH:63][cH:64]4)[CH2:52][CH:53]3[OH:54])[n:44][c:45]2[CH2:46][CH3:47])[cH:35][cH:36][c:37]([Cl:39])[cH:38]1.[F:67][CH2:68][CH2:69][Br:70]>>[Cl:32][c:33]1[c:34](-[c:40]2[n:41][c:42]([CH2:65][CH3:66])[c:43]([NH:48][CH:49]3[CH2:50][N:51]([C:55](=[O:56])[O:57][CH2:58][c:59]4[cH:60][cH:61][cH:62][cH:63][cH:64]4)[CH2:52][CH:53]3[O:54][CH2:69][CH2:68][F:67])[n:44][c:45]2[CH2:46][CH3:47])[cH:35][cH:36][c:37]([Cl:39])[cH:38]1

Participants

4

Reactant 3

HCID 129822-Fluoroethyl bromideHCID 22147271HCID 22147271, compoundHCID 221473105-(2,4-dichlorophenyl)-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine

Product 1

HCID 22147410Benzyl 3-[[5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-yl]amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-8ddc64bdc68540648efdf70030430365
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…