Thiopheneethanamine → HCID 46932520, compound

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Reaction Steps

Prepared according to the procedure described for example 50 from 5-[(3,5-dichloro-4-pyridyl)sulfanyl]-4-nitro-thiophene-2-carboxylic acid (100 mg, 0.28 mmol) and Thiophene-2-ethylamine (41 mg, 0.32 mmol). The title compound was obtained as a solid (35 mg, 27% yield). 1H NMR (400 MHz, d6-DMSO) δ: 9.00 (1H, m), 8.99 (2H, m), 8.41 (1H, s), 7.33 (1H, m), 6.94 (2H, m), 3.44 (2H, m), 3.02 (2H, m). MS m/z: 458.00, 459.99 [M+H]+.

Provenance & Evidence